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New Cardiovascular-Kidney-Metabolic Syndrome (CKM) Unveiled as a Link between Obesity, Diabetes, and Kidney Disease

by Kaia

The American Heart Association has introduced a groundbreaking medical concept, the Cardiovascular-Kidney-Metabolic Syndrome (CKM), acknowledging the interwoven relationships between obesity, diabetes, and heart and kidney diseases. This recognition comes as an increasing number of Americans are grappling with multiple chronic health issues at younger ages.

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According to a recent advisory release, the objective of identifying CKM is to enable earlier diagnosis and intervention for individuals at high risk of cardiovascular disease-related mortality.

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Dr. Chiadi E. Ndumele, Director of Obesity and Cardiometabolic Research in the Division of Cardiology at Johns Hopkins University and lead author of the advisory, stated, “Reducing the pipeline of individuals progressing to heart disease is our primary goal.” He emphasized the pressing need to address the health consequences resulting from the intricate interplay of these conditions, underscoring the importance of naming and defining CKM as a pivotal paradigm shift.

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Emerging evidence demonstrates how metabolic risk factors, including abdominal fat, high blood pressure, elevated cholesterol levels, and hyperglycemia, can have detrimental effects on various organs in the body. CKM aims to recognize and address these connections comprehensively.

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Dr. Pam R. Taub, a cardiologist and professor of medicine at the UC San Diego School of Medicine, believes this new approach could be a “game changer” in patient care. She highlighted the role of novel medications in treating conditions within the syndrome, such as kidney disease, diabetes, and obesity. These treatments have not only reduced cardiovascular events but also provided fresh insights into the intricate interactions among different organs in the body.

Taub emphasized the significance of early detection, citing the example of identifying early-stage kidney disease through urine samples. Timely intervention with appropriate medications can prevent the progression of kidney disease, highlighting the potential for significant positive health outcomes.

In essence, when considering the body’s organs collectively, early disease detection becomes feasible, leading to the prevention of adverse cardiovascular events such as heart failure, heart attacks, and stroke.

The recognition of CKM marks a significant step towards a more integrated and proactive approach to healthcare, where understanding the interconnectedness of various health factors can lead to improved patient outcomes and a reduction in the burden of cardiovascular diseases. It is anticipated that this innovative perspective will guide future research and medical practices in managing complex health conditions effectively.

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