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Ancient Herb Shows Potential in Fighting Dementia

by Kaia

Researchers at Osaka Metropolitan University have uncovered promising results in the search for preventive treatments for dementia. Led by Professor Takami Tomiyama, the team discovered that Ziziphus jujuba Miller var. spinosa, a variety of jujube used in traditional Chinese medicine, may help restore cognitive and motor functions in mice models.

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The study involved administering hot water extracts of the jujube seeds to mice suffering from Alzheimer’s disease, frontotemporal dementia, Parkinson’s disease, and dementia with Lewy bodies. The results showed significant improvements in both cognitive and motor functions.

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Additionally, when the seeds were crushed into powder and given to the mice, the team observed that the cognitive performance of the mice improved beyond that of the control group. The powdered seeds also appeared to slow cellular aging in older mice, enhancing their cognitive abilities to levels similar to younger animals.

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This research follows previous studies by the team, which demonstrated improvements in dementia-related pathology and motor function using other traditional herbs, including Hawaiian mamaki and Chinese Acorus gramineus.

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