Social media has sparked discussions around Mucinex, a well-known cold and flu medication, with some women claiming it has aided in conception.
In a viral TikTok post, Amanda MacGibbon shared her experience of taking Mucinex shortly before trying to conceive. She combined it with coenzyme Q10 and metformin, a medication for polycystic ovary syndrome. MacGibbon announced she is expecting a baby in October.
Another TikTok user claimed success after taking Mucinex 12-hour pills just before intercourse during her fertile window. “We are pregnant, and I’m 35 years old and have tried for two years,” she said.
Mucinex contains guaifenesin, which is known to thin mucus and alleviate chest congestion. However, there is no scientific proof that it affects cervical mucus, which plays a role in helping sperm reach the egg.
Dr. Jessica Shepherd, a board-certified OB-GYN, addressed the issue on “Good Morning America.” She stated that studies have not shown a significant improvement in cervical mucus quality with Mucinex, nor its effect on sperm motility. “Women can try it on their own, but there’s no strong data to support an increase in fertility chances,” she noted.
Dr. Karen Tang, a gynecologic surgeon, referred to a 1982 study where half of 40 couples with infertility reported better sperm motility after taking guaifenesin. However, she emphasized the lack of a placebo group, suggesting the results could be coincidental. “That’s why we don’t prescribe Mucinex to those trying to conceive,” she explained in an April TikTok.
Despite these claims, Dr. Tang acknowledged that anecdotal evidence could warrant further investigation.
The manufacturer of Mucinex, Reckitt, cautioned that using the medication for infertility is considered off-label. In a statement to “Good Morning America,” the company advised, “Taking any medications outside their approved indications may be harmful.” They recommend consulting a healthcare professional and reading product labels carefully.
Guaifenesin may have side effects, including dizziness, constipation, headaches, fatigue, and rashes, as noted by the Cleveland Clinic. The U.S. Food and Drug Administration approved guaifenesin for over-the-counter use many years ago.
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